Start by making the seasoning rub. Combine all of the rub ingredients together in a small bowl and mix well.
Season the chicken with the rub, making sure every bit of the chicken is covered liberally.
Next, chop up the butternut squash and brussels and place in a bowl. Toss in the avocado oil, salt, pepper, garlic powder and chili powder. Mix well to incorporate the seasonings and spread out in an even layer on a baking sheet. Set aside.
Preheat oven to 425 degrees Fahrenheit.
Heat a cast iron skillet over medium heat and add in the fat. Let the skillet warm up to full temperature.
Add in your chicken to cook for 5 minutes. Flip it over to the other side and cook for another 5 minutes.
Add the squash and brussels to the skillet around the chicken. Carefully transfer the skillet to the oven using oven mitts.
Cook for 30 minutes and remove everything from the oven. Allow to cool for a few minutes before serving.
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